Understanding the seminal plasma proteome and its role in male fertility
Seminal plasma legal definition of seminal plasma
Human seminal plasma contains a variety of macro and trace elements including magnesium Mg , copper Cu , zinc Zn , and iron Fe that have essential roles in normal functioning of semen and its quality. The imbalance of these elements has been reported in several pathologic and male infertility disorders. Therefore, this study aimed to determine the levels of these elements in seminal plasma samples, their relationships with each other and their impact on sperm motility. Overall, males 96 normospermic and 96 asthenospermic males were enrolled in the study. The samples were centrifuged and seminal levels of Mg, Cu, Zn and Fe were measured using atomic absorption spectroscopy. The levels of Zn did not differ between the two groups, while the levels of Mg, Cu, and Fe were significantly higher in normospermic males.
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4.2 Getting the spermatozoa ready
Seminal plasma SP plays an important role in the motility, viability and maintenance of the fertilizing capacity of mammalian spermatozoa. This study is the first on brown bear Ursus arctos SP components, and has two main objectives: 1 to define the SP composition in bear ejaculate and 2 to identify variations in SP composition in relation to high and low levels of testosterone in serum during the breeding season. The biochemical and protein compositions of the SP samples were assessed, and sperm motility was analyzed.
Most cells develop and survive a changing environment through intracellular and extracellular signals that drive gene expression and the production of new proteins Davies For example, heat stress may induce the expression of heat shock proteins that help to refold proteins damaged by an increase in temperature. Spermatozoa are unique in this regard because they are rendered transcriptionally and translationally silent well before they become temporally or spatially competent to fertilise.